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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PEX1
All Species:
16.06
Human Site:
T181
Identified Species:
22.08
UniProt:
O43933
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43933
NP_000457.1
1283
142867
T181
K
L
L
I
Q
P
K
T
R
R
A
K
E
N
T
Chimpanzee
Pan troglodytes
XP_519198
1283
142803
T181
K
L
L
I
Q
P
K
T
R
R
A
K
E
N
T
Rhesus Macaque
Macaca mulatta
XP_001101055
1278
142022
T181
K
L
L
I
Q
P
K
T
R
Q
T
K
E
N
T
Dog
Lupus familis
XP_532459
1267
140567
G167
L
M
P
T
A
A
Y
G
R
L
E
T
D
T
K
Cat
Felis silvestris
Mouse
Mus musculus
Q5BL07
1284
141409
T181
K
L
L
I
Q
P
K
T
R
Q
A
K
E
S
T
Rat
Rattus norvegicus
P46462
806
89330
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520628
1178
126535
L162
S
S
L
E
Q
H
L
L
D
Q
I
R
I
V
F
Chicken
Gallus gallus
XP_418655
1290
143066
L184
I
C
P
K
A
R
E
L
E
E
N
I
I
D
M
Frog
Xenopus laevis
P23787
805
89193
Zebra Danio
Brachydanio rerio
Q7ZU99
806
89405
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KN62
801
88841
Honey Bee
Apis mellifera
XP_397107
1069
120490
N83
V
I
V
S
F
V
K
N
V
P
I
L
I
K
I
Nematode Worm
Caenorhab. elegans
P54812
810
89622
Sea Urchin
Strong. purpuratus
XP_797089
1508
166130
E257
V
S
K
P
E
E
G
E
T
N
I
P
S
M
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SCN8
815
90322
Baker's Yeast
Sacchar. cerevisiae
P24004
1043
117258
P57
H
S
H
N
S
D
I
P
I
V
H
L
G
W
D
Red Bread Mold
Neurospora crassa
Q7SGP2
1381
148356
T249
I
I
V
S
R
V
R
T
S
K
T
K
R
S
S
Conservation
Percent
Protein Identity:
100
99.6
92.8
86.4
N.A.
82
23.3
N.A.
52.4
62.4
22.9
22.8
N.A.
23.6
27.6
22.1
35.2
Protein Similarity:
100
100
94.9
92
N.A.
89.5
39.2
N.A.
66
77.6
38.6
39
N.A.
37.6
46.7
38.4
53.2
P-Site Identity:
100
100
86.6
6.6
N.A.
86.6
0
N.A.
13.3
0
0
0
N.A.
0
6.6
0
0
P-Site Similarity:
100
100
93.3
20
N.A.
100
0
N.A.
26.6
13.3
0
0
N.A.
0
20
0
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.5
25.7
21.4
Protein Similarity:
N.A.
N.A.
N.A.
38.5
45.2
40.9
P-Site Identity:
N.A.
N.A.
N.A.
0
0
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
0
0
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
12
6
0
0
0
0
18
0
0
0
0
% A
% Cys:
0
6
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
6
0
0
6
0
0
0
6
6
6
% D
% Glu:
0
0
0
6
6
6
6
6
6
6
6
0
24
0
0
% E
% Phe:
0
0
0
0
6
0
0
0
0
0
0
0
0
0
6
% F
% Gly:
0
0
0
0
0
0
6
6
0
0
0
0
6
0
0
% G
% His:
6
0
6
0
0
6
0
0
0
0
6
0
0
0
0
% H
% Ile:
12
12
0
24
0
0
6
0
6
0
18
6
18
0
6
% I
% Lys:
24
0
6
6
0
0
30
0
0
6
0
30
0
6
6
% K
% Leu:
6
24
30
0
0
0
6
12
0
6
0
12
0
0
0
% L
% Met:
0
6
0
0
0
0
0
0
0
0
0
0
0
6
6
% M
% Asn:
0
0
0
6
0
0
0
6
0
6
6
0
0
18
0
% N
% Pro:
0
0
12
6
0
24
0
6
0
6
0
6
0
0
6
% P
% Gln:
0
0
0
0
30
0
0
0
0
18
0
0
0
0
0
% Q
% Arg:
0
0
0
0
6
6
6
0
30
12
0
6
6
0
0
% R
% Ser:
6
18
0
12
6
0
0
0
6
0
0
0
6
12
6
% S
% Thr:
0
0
0
6
0
0
0
30
6
0
12
6
0
6
24
% T
% Val:
12
0
12
0
0
12
0
0
6
6
0
0
0
6
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
6
0
% W
% Tyr:
0
0
0
0
0
0
6
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _